KPV – Anti-Inflammatory Powerhouse for Gut, Skin, and Systemic Recovery

Your Ultimate Peptide for Inflammation, Immunity, and Recovery

KPV (Lysine–Proline–Valine) is a tripeptide fragment of alpha-MSH with powerful anti-inflammatory and immune-modulating effects. Unlike corticosteroids or NSAIDs, KPV works by targeting inflammation at the cellular signaling level without broadly suppressing the immune system.

It is used in clinical protocols for gut healing, skin repair, neuroimmune regulation, and systemic inflammation control.

Key Benefits

Targeted Anti-Inflammatory Action

• Inhibits NF-κB and pro-inflammatory cytokines such as TNF-α and IL-6.

• Promotes resolution of inflammation without the risks of steroids.

• Reference: Catania et al., 2010 – Reduced colitis severity and epithelial injury with KPV administration.

Supports Gut Barrier and Mucosal Healing

• Strengthens intestinal barrier integrity and supports mucosal regeneration.

• Effective in conditions such as IBD, leaky gut, and autoimmune GI dysfunction.

• Reference: Getting et al., 2008 – Accelerated mucosal healing and cytokine reduction in models of colitis.

Immune Modulation Without Suppression

• Works through melanocortin receptor pathways.

• Maintains host defense while regulating excess inflammation.

• Reference: Catania & Lipton, 2003 – Review of selective anti-inflammatory actions of KPV.

Skin Repair and Inflammation Control

• Demonstrated benefit in eczema, psoriasis, and wound healing.

• Reduces inflammatory mediators while stimulating regenerative pathways.

• Reference: Delgado et al., 2009 – Topical KPV reduced inflammatory skin lesions.

Stacking Synergy

KPV works best when combined with complementary peptides for comprehensive recovery:

• BPC-157: Accelerates GI, joint, and soft tissue healing.

• TB-500: Promotes systemic anti-inflammation and muscle recovery.

• GHK-Cu: Enhances skin regeneration and collagen synthesis.

• DSIP or Selank: Supports neuroimmune balance and stress-related inflammation.

Who Should Consider KPV

• Individuals with chronic gut or skin inflammation.

• Athletes or patients with systemic inflammatory conditions.

• Those seeking a non-steroidal, immune-modulating option.

• Clinicians building recovery protocols for optimized healing.

What You Receive with Every Order

Each KPV purchase from PROpeptides includes:

• 1 x 10mg lyophilized peptide vial.

• Pre-measured bacteriostatic water for safe reconstitution.

• Insulin syringes and alcohol swabs.

• Sharps container disposal bag.

• Comprehensive dosing and safety instructions.

• Free telemedicine consultation with licensed medical providers through Arizona Sports Medicine.

Prescription & Compliance Information

KPV is prescription-only and dispensed under Arizona Sports Medicine.

• All new patients complete a secure telemedicine consultation prior to shipment.

• Prescriptions are issued only when medically appropriate.

• Existing patients may reorder without repeating intake.

• Orders are processed only after a valid provider–patient relationship is established.

Off-Label Use Statement

Arizona Sports Medicine and its affiliated providers may prescribe peptides such as KPV for off-label use when clinically appropriate.

• This practice is common and legal in modern medicine.

• Supported by emerging clinical evidence and peer-reviewed studies.

• Guided by provider expertise, patient-specific needs, and informed consent.

Contact Information

• Email: Admin@ArizonaSportsMed.com

• Phone/Text: 480-400-6225

Science-Driven Healing. Patient-First Care.

KPV is a cornerstone peptide for targeted inflammation control, gut and skin support, and systemic immune regulation. With PROpeptides, you receive clinical oversight and safe, evidence-based access to modern peptide science.