GL-3 Molecule (Prescription Only) – 60mg / 5mL

Triple-Incretin Therapy for Maximum Fat Loss, Appetite Control & Metabolic Optimization

Formulation

GL-3 Core 60

1 × 60mg GL-3 Multi-Dose Vial

Each vial contains:

• 60mg GL-3

• 5mL total volume

• Concentration: 12mg/mL

Total Package Contents: 60mg GL-3 (5mL Total)

Classification: Prescription Only – Requires Provider Consultation & Approval

What Is GL-3 Therapy?

GL-3 is a prescription triple-incretin therapy that activates three key metabolic pathways:

• GLP-1 (Glucagon-Like Peptide-1)

• GIP (Glucose-Dependent Insulinotropic Polypeptide)

• Glucagon Receptor

By targeting all three receptors simultaneously, GL-3 provides comprehensive metabolic signaling, leading to:

✔ Significant appetite suppression

✔ Accelerated fat loss

✔ Improved insulin sensitivity

✔ Increased energy expenditure

✔ Enhanced metabolic flexibility

✔ Long-term body composition improvements

GL-3 represents the most advanced tier of incretin-based therapy and is typically utilized for patients requiring longer-term, provider-directed metabolic intervention and sustained fat loss.

All GL-3 products require clinical consultation and prescription approval prior to dispensing.

🔬 Key Research-Based Mechanisms

🔥 Triple-Incretin Activation for Superior Fat Loss

Simultaneous activation of GLP-1, GIP, and glucagon receptors enhances satiety and drives adipose tissue reduction.

Jastreboff et al., 2023 (NEJM) – Demonstrated up to 24.2% total body-weight reduction over 48 weeks.

🩸 Improved Glycemic Control & Insulin Sensitivity

Reduces fasting glucose, improves insulin signaling, and lowers HbA1c.

Frias et al., 2023 (Diabetes Care) – Reported HbA1c reductions up to 2.2%.

🧠 Appetite Suppression & Craving Control

Reduces central appetite signaling and food reward pathways.

Killion et al., 2022 – Demonstrated reduced hedonic eating behavior in preclinical models.

🧬 Increased Fat Oxidation & Energy Expenditure

Glucagon receptor activation increases metabolic rate and fat utilization.

Gil-Lozano et al., 2021 – Showed preservation of metabolic rate with increased fat oxidation.

⚕️ Clinical Access & Prescription Protocol

GL-3 therapy requires provider oversight and prescription approval.

✔ Telehealth consultation required prior to dispensing

✔ Labs may be recommended (HbA1c, fasting glucose, lipid panel, CMP)

✔ Individualized dosing and titration plan

✔ Ongoing provider monitoring and follow-up included

💉 Dosing Protocol (GL-3 Core 60)

Total Dose

60mg Total GL-3

Package Contents

1 × 60mg / 5mL vial

Concentration

12mg/mL

Dosing Equivalency

Starting Dose

17 Units Weekly (~2mg)

Titration Strategy (Standard PROPeptides Protocol)

✔ Begin at 17 units weekly

✔ Maintain dose until 2 consecutive weeks of no meaningful weight loss

✔ Increase by approximately 8–9 units (~1mg) when appropriate

✔ If side effects occur, reduce dose by approximately 8–9 units and resume titration after symptoms resolve

Administration

Route: Subcutaneous injection

Preferred Site: Abdomen

Frequency: Once weekly

Ideal Use

The GL-3 Core 60 vial is designed for patients who have advanced beyond starter dosing and are maintaining moderate to higher weekly doses.

Typical utilization:

• 4mg weekly (33 units) = approximately 15 weeks

• 5mg weekly (42 units) = approximately 12 weeks

• 6mg weekly (50 units) = approximately 10 weeks

• 8mg weekly (67 units) = approximately 7–8 weeks

Actual duration varies based on provider-directed titration and individual response.

Program Length

Typically utilized as part of a 3–12 month provider-guided metabolic optimization program with reassessment every 4–8 weeks.

Compatible Stacks

KPV

Supports gut health and inflammation management.

Tesamorelin

May support body composition optimization and visceral fat reduction.

MOTS-C

Supports metabolic efficiency and insulin sensitivity.

GHK-Cu

Supports recovery and tissue support.

📦 What’s Included With Every Order

✔ 1 × 60mg / 5mL GL-3 vial

✔ Insulin syringes & alcohol swabs

✔ Sharps container bag

✔ Printed dosing, titration, storage, and injection guide

✔ Ongoing access to licensed prescribing provider

✔ Free telemedicine consultation through Arizona Sports Medicine

📧 Need Assistance?

Admin@Propeptides.com

480-400-6225

🛡️ Maximum Potency. Triple-Pathway Precision. Clinical Oversight.

GL-3 Core 60 is designed for patients seeking long-term metabolic optimization with the convenience of a high-capacity multi-dose vial. Through triple-incretin activation and provider-guided dosing, GL-3 supports meaningful fat loss, appetite control, improved insulin sensitivity, and sustained body composition improvements.

Commit to GL-3 Core 60 for advanced metabolic support, extended supply, and provider-guided weight loss optimization.