GHK-Cu – Skin, Hair & Tissue Remodeling Peptide

(Copper Tripeptide-1)

Formulation (per vial):

• GHK-Cu – 50 mg

Classification: Non-Prescription Peptide

What Is It?

GHK-Cu (Copper Tripeptide-1) is a naturally occurring peptide found in human plasma, saliva, and urine, with levels that decline significantly with age. It is one of the most extensively studied regenerative peptides, known for its ability to stimulate collagen production, remodel tissue, and improve skin and hair health.

• Skin & Anti-Aging: Restores youthful gene expression, improves elasticity, and reduces wrinkles.

• Hair Regeneration: Reactivates dormant follicles, supporting thicker and stronger hair growth.

• Tissue Remodeling: Enhances wound healing, reduces scar formation, and supports vascular health.

Key References:

• Pickart et al., J Biomater Tissue Eng. 2012 – Wound healing and anti-inflammatory effects.

• Maquart et al., Ann N Y Acad Sci. 1988 – Collagen synthesis stimulation.

• Pickart et al., BioMed Res Int. 2015 – Role in gene expression, skin rejuvenation, and hair growth.

Who Should Use It?

• Individuals pursuing skin rejuvenation and anti-aging support.

• Those experiencing hair thinning or loss.

• Patients seeking scar reduction or wound healing benefits.

• Athletes or individuals focused on vascular recovery and cosmetic optimization.

Key Benefits

• Collagen Remodeling: Stimulates type I collagen and extracellular matrix repair.

• Skin Rejuvenation: Improves elasticity, reduces fine lines, and restores tone.

• Hair Growth: Activates follicle regeneration for thicker hair.

• Scar Reduction: Promotes healing with minimal fibrotic tissue.

• Inflammation Balance: Reduces cytokine-driven skin and tissue irritation.

Protocol Options

1-Month Reset Protocol

• Use Case: Post-procedure support or quick cosmetic boost.

• Structure: Daily or 5x/week for 4 weeks → 4 weeks off.

• Benefits: Early improvements in skin texture, tone, and recovery.

3-Month Regeneration Protocol

• Use Case: Hair regrowth, anti-aging cycle, scar remodeling.

• Structure: 12 weeks on → 30-day break.

• Benefits: Noticeable wrinkle reduction, improved collagen, enhanced follicle activity.

6-Month Advanced Protocol

• Use Case: Long-term skin and hair support.

• Structure: Two 12-week cycles with a 30-day break between.

• Benefits: Deep collagen remodeling, long-lasting rejuvenation, sustained hair improvements.

Dosage & Timing

• Standard Dosing: 10–20 units per injection (≈1–2 mg).

• Frequency: Daily or 5x/week depending on goals.

• Cycle Length: 4–12 weeks typical, cycled with breaks.

Preparation & Storage

• Reconstitution: Add 2–3 mL bacteriostatic water per vial.

• Route: Subcutaneous injection (abdomen or back of arm).

• Storage: Refrigerate after reconstitution; discard after 30 days.

Onset & Duration

• Onset: Cosmetic improvements visible within 4 weeks.

• Duration: Structural remodeling and hair results more prominent after 8–12 weeks.

Risks & Considerations

Possible Side Effects:

• Temporary injection site redness or irritation.

• Rare systemic effects (headache, mild fatigue) at high doses.

• Very rare copper overload symptoms if misused.

Contraindications:

• Copper metabolism disorders (e.g., Wilson’s disease).

• Use caution in patients with chronic systemic illness without medical oversight.

Key Takeaways

• GHK-Cu is one of the most well-documented regenerative peptides, with decades of research supporting its cosmetic and tissue-repair benefits.

• Flexible 1-, 3-, and 6-month protocols allow for short-term recovery or long-term rejuvenation.

• Pairs well with regenerative therapies like microneedling, PRP, or laser treatments for enhanced results.

• Safe for cosmetic and recovery purposes without prescription status.